Exploring the Gap: An Expliration of the Difference in INcome Received from Wages and Salaries by Women and Men in Full-Time Employment

The difference between the income received by employed women and men in New Zealand is widely recognised. Often referred to as the "gender wage gap"1 , this income differential has prevailed despite significant improvements in the past 50 years including changes in society's attitudes towards women in employment and increasing numbers of women in paid work. What then can this difference be attributed to? Is it structural factors such as age and occupation, or are there other un-measurable factors at work? Confining itself to the wages and salaries of women and men in full-time employment, this paper presents some of the results of recent analysis conducted by Statistics New Zealand's Analytical Support Division. Using data from the 1997 New Zealand Income Survey and several different multivariate techniques, this analysis attempts to explore some of the factors behind this "earnings gap". Originally conducted for an upcoming Statistics New Zealand analytical publication, this research first explores the factors responsible for prescribing the level of earnings for all people then applies these results in a process of standardisation. The results leave much scope for both discussion and a continuation of analysis

An Inquiry into the Antecedents of Consumer Purchase of Non-Deceptive Counterfeit Goods: Theory, Practice and Problems

With counterfeit good consumption growing at alarming rates each year, this topic is increasingly demanding attention of marketing academics. This dissertation examines two sets of factors that influence consumer attitude toward counterfeits: sociocultural influences and psychological influences. Based on a review of the literature, two constructs, namely information susceptibility and normative susceptibility are combined to form a group of sociocultural influences expected to influence consumer attitude toward counterfeits. In addition, five constructs are combined to represent psychological influences, namely value consciousness, self-identity, integrity, materialism and perceived risk. Data was collected through a web-based survey and features a cross-sectional design. Utilizing a sample of 228 respondents, confirmatory factor analysis coupled with structural equation modeling was employed to analyze hypothesized relationships. Results suggest the most significant influence on consumer attitude toward counterfeits is integrity the more integrity held by a consumer, the less favorable their attitude toward counterfeits. In addition, materialism and normative susceptibility were also found to be positively related to consumer attitude toward counterfeits. Consumer attitude toward counterfeits was also shown to have positive significance as a mediating variable between the antecedents and purchase intention. The results of this dissertation suggest that consumers, and their reference groups justify purchasing counterfeit items due to what they believe to be unfair business practices such as charging too much. This research will assist scholars, marketers, and government agencies to understand the implications of counterfeit good consumption and contribute to the development of effective strategies to counter the purchase of non-deceptive counterfeit good

The Counterfeit Conundrum: A Case Study to Examine the Best Way to Combat Counterfeit Consumption

Estimated at more than $500 billion, counterfeits are a booming industry. The negative impacts can no longer be ignored. As evidenced by the industry growth, efforts to combat consumption of counterfeit products have largely failed. This case study examines the counterfeit industry and a campaign developed by the U.S. Customs and Border Protection Agency. It presents the reader the opportunity to contemplate viable solutions for ending counterfeit consumption

Exploring the Gap: An Expliration of the Difference in INcome Received from Wages and Salaries by Women and Men in Full-Time Employment

The difference between the income received by employed women and men in New Zealand is widely recognised. Often referred to as the "gender wage gap"1 , this income differential has prevailed despite significant improvements in the past 50 years including changes in society's attitudes towards women in employment and increasing numbers of women in paid work. What then can this difference be attributed to? Is it structural factors such as age and occupation, or are there other un-measurable factors at work? Confining itself to the wages and salaries of women and men in full-time employment, this paper presents some of the results of recent analysis conducted by Statistics New Zealand's Analytical Support Division. Using data from the 1997 New Zealand Income Survey and several different multivariate techniques, this analysis attempts to explore some of the factors behind this "earnings gap". Originally conducted for an upcoming Statistics New Zealand analytical publication, this research first explores the factors responsible for prescribing the level of earnings for all people then applies these results in a process of standardisation. The results leave much scope for both discussion and a continuation of analysis

High-throughput screen of drug repurposing library identifies inhibitors of Sarcocystis neurona growth

The apicomplexan parasite Sarcocystis neurona is the primary etiologic agent of equine protozoal myeloencephalitis (EPM), a serious neurologic disease of horses. Many horses in the U.S. are at risk of developing EPM; approximately 50% of all horses in the U.S. have been exposed to S. neurona and treatments for EPM are 60-70% effective. Advancement of treatment requires new technology to identify new drugs for EPM. To address this critical need, we developed, validated, and implemented a high-throughput screen to test 725 FDA-approved compounds from the NIH clinical collections library for anti-S. neurona activity. Our screen identified 18 compounds with confirmed inhibitory activity against S. neurona growth, including compounds active in the nM concentration range. Many identified inhibitory compounds have well-defined mechanisms of action, making them useful tools to study parasite biology in addition to being potential therapeutic agents. In comparing the activity of inhibitory compounds identified by our screen to that of other screens against other apicomplexan parasites, we found that most compounds (15/18; 83%) have activity against one or more related apicomplexans. Interestingly, nearly half (44%; 8/18) of the inhibitory compounds have reported activity against dopamine receptors. We also found that dantrolene, a compound already formulated for horses with a peak plasma concentration of 37.8 ± 12.8 ng/ml after 500 mg dose, inhibits S. neurona parasites at low concentrations (0.065 μM [0.036-0.12; 95% CI] or 21.9 ng/ml [12.1-40.3; 95% CI]). These studies demonstrate the use of a new tool for discovering new chemotherapeutic agents for EPM and potentially providing new reagents to elucidate biologic pathways required for successful S. neurona infection

Preventing foot ulceration in diabetes:systematic review and meta-analyses of RCT data

Aims/hypothesis: Foot ulceration is a serious complication for people with diabetes that results in high levels of morbidity for individuals and significant costs for health and social care systems. Nineteen systematic reviews of preventative interventions have been published, but none provides a reliable numerical summary of treatment effects. The aim of this study was to systematically review the evidence from RCTs and, where possible, conduct meta-analyses to make the best possible use of the currently available data. Methods: We conducted a systematic review and meta-analysis of RCTs of preventative interventions for foot ulceration. OVID MEDLINE and EMBASE were searched to February 2019 and the Cochrane Central Register of Controlled Trials to October 2018. RCTs of interventions to prevent foot ulcers in people with diabetes who were free from foot ulceration at trial entry were included. Two independent reviewers read the full-text articles and extracted data. The quality of trial reporting was assessed using the Cochrane Risk of Bias tool. The primary outcome of foot ulceration was summarised using pooled relative risks in meta-analyses. Results: Twenty-two RCTs of eight interventions were eligible for analysis. One trial of digital silicone devices (RR 0.07 [95% CI 0.01, 0.55]) and meta-analyses of dermal infrared thermometry (RR 0.41 [95% CI 0.19, 0.86]), complex interventions (RR 0.59 [95% CI 0.38, 0.90], and custom-made footwear and offloading insoles (RR 0.53 [95% CI 0.33, 0.85]) showed beneficial effects for these interventions. Conclusions/interpretation: Four interventions were identified as being effective in preventing foot ulcers in people with diabetes, but uncertainty remains about what works and who is most likely to benefit

Trends in all cause and viral liver disease-related hospitalizations in people with hepatitis B or C: a population-based linkage study

<p>Abstract</p> <p>Background</p> <p>Previous studies have reported an excess burden of cancer and mortality in populations with chronic hepatitis B (HBV) or C (HCV), but there are limited data comparing hospitalization rates. In this study, we compared hospitalization rates for all causes and viral liver disease in people notified with HBV or HCV in New South Wales (NSW), Australia.</p> <p>Methods</p> <p>HBV and HCV notifications were linked to their hospital (July 2000-June 2006), HIV and death records. Standardized hospitalization ratios (SHRs) were calculated using rates for the NSW population. Random effects Poisson regression was used to examine temporal trends.</p> <p>Results</p> <p>The SHR for all causes and non alcoholic liver disease was two-fold higher in the HCV cohort compared with the HBV cohort (SHRs 1.4 (95%CI: 1.4-1.4) v 0.6 (95%CI: 0.6-0.6) and 14.0 (95%CI: 12.7-15.4) v 5.4 (95%CI: 4.5-6.4), respectively), whilst the opposite was seen for primary liver cancer (SHRs 16.2 (95%CI: 13.8-19.1) v 29.1 (95%CI: 24.7-34.2)). HIV co-infection doubled the SHR except for primary liver cancer in the HCV/HIV cohort. In HBV and HCV mono-infected cohorts, all cause hospitalization rates declined and primary liver cancer rates increased, whilst rates for non alcoholic liver disease increased by 9% in the HCV cohort but decreased by 14% in the HBV cohort (<it>P </it>< 0.001).</p> <p>Conclusion</p> <p>Hospital-related morbidity overall and for non alcoholic liver disease was considerably higher for HCV than HBV. Improved treatment of advanced HBV-related liver disease may explain why HBV liver-related morbidity declined. In contrast, HCV liver-related morbidity increased and improved treatments, especially for advanced liver disease, and higher levels of treatment uptake are required to reverse this trend.</p